Taking your probiotics when your stomach acid levels are lower can help ensure that more healthy bacteria survive and colonize the gut, where they can make a meaningful impact on your gut health and immune system.
So, when exactly is that? While day or night doesn’t really matter, a number of experts, including Dr. Pedre and David Perlmutter, M.D., advise taking probiotics on an empty stomach—your stomach churns out more acid to digest the food you eat, after all.
Research seems to support these recommendations as well, with one study finding that probiotics given 30 minutes before a meal or at the beginning of a meal were much more likely to survive than probiotics given 30 minutes after a meal, when digestion is in full swing.
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